TBP anticorps (AA 38-107)

N° du produit ABIN5692949

Cet anticorps anti-TBP est un anticorps Lapin Polyclonal détectant TBP dans WB et ELISA. Adapté pour Souris et Rat.

Aperçu rapide pour TBP anticorps (AA 38-107) (ABIN5692949)

Antigène: TBP (TATA Box Binding Protein (TBP))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TBP anticorps

Épitope: AA 38-107

Fonction: Anti-TATA binding protein TBP Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TATA binding protein TBP Antibody Picoband® (ABIN5692949). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogène: E. coli-derived mouse Tbp recombinant protein (Position: L38-A107).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Bauer, P., Laccone, F., Rolfs, A., Wullner, U., Bosch, S., Peters, H., Liebscher, S., Scheible, M., Epplen, J. T., Weber, B. H. F., Holinski-Feder, E., Weirich-Schwaiger, H., Morris-Rosendahl, D. J., Andrich, J., Riess, O.Trinucleotide repeat expansion in SCA17/TBP in white patients with Huntington's disease-like phenotype.J. Med. Genet. 41: 230-232, 2004. 2. Stevanin, G., Fujigasaki, H., Lebre, A.-S., Camuzat, A., Jeannequin, C., Dode, C., Takahashi, J., San, C., Bellance, R., Brice, A., Durr, A.Huntington's disease-like phenotype due to trinucleotide repeat expansions in the TBP and JPH3 genes.Brain 126: 1599-1603, 2003. 3. Veenstra, G. J. C., Weeks, D. L., Wolffe, A. P.Distinct roles for TBP and TBP-like factor in early embryonic gene transcription in Xenopus.Science 290: 2312-2314, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur TBP

Antigène: TBP (TATA Box Binding Protein (TBP))

Autre désignation: Tbp

Sujet:

Synonyms: TATA-box-binding protein, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit, Tbp, Tfiid

Tissue Specificity: Ubiquitously expressed.

Background: TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20 % of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.

Poids moléculaire: 38 kDa

ID gène: 21374

UniProt: P29037

Pathways: Signalisation WNT