Thrombopoietin anticorps (AA 27-259)

N° du produit ABIN5692952

Détail du produit anti-Thrombopoietin anticorps

Antigène: Thrombopoietin (THPO)

Épitope: AA 27-259

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombopoietin est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Thrombopoietin detection. Tested with WB, Direct ELISA in Mouse,Rat.

Immunogène: E. coli-derived rat Thrombopoietin recombinant protein (Position: A27-H259).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: THPO (THPO Produits)

Synonymes: anticorps MGDF, anticorps MKCSF, anticorps ML, anticorps MPLLG, anticorps THCYT1, anticorps TPO, anticorps Mgdf, anticorps Ml, anticorps Mpllg, anticorps Tpo, anticorps Tpo1, anticorps Tpo2, anticorps Tpo3, anticorps Tpo4, anticorps tpo, anticorps LOC100231762, anticorps thrombopoietin, anticorps THPO, anticorps Thpo, anticorps thpo

Sujet:

Synonyms: Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand, THPO, MGDF

Background: Thrombopoietin (THPO), also known as megakaryocyte growth and development factor (MGDF), is a protein that in humans is encoded by the THPO gene. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.

UniProt: P40225

Pathways: Signalistation JAK/STAT, Hormone Activity