Kallikrein 1 anticorps (AA 25-262)

N° du produit ABIN5693026

Détail du produit anti-Kallikrein 1 anticorps

Antigène: Kallikrein 1 (KLK1)

Épitope: AA 25-262

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Kallikrein 1 detection. Tested with WB, ELISA(Cap) in Human.

Immunogène: E. coli-derived human Kallikrein 1 recombinant protein (Position: I25-S262).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Kallikrein 1 (ABIN5693026)

Zhang, Xu, Zhao, Chen: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." dans: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).

Lin, Lin, Chung, Vonderfecht, Camden, Flodby, Borok, Limesand, Mizushima, Ann: "Dynamic involvement of ATG5 in cellular stress responses." dans: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).

Détails sur Kallikrein 1

Antigène: Kallikrein 1 (KLK1)

Autre désignation: KLK1 (KLK1 Produits)

Synonymes: anticorps KLKR, anticorps Klk6, anticorps hK1, anticorps klkr, anticorps kallikrein, anticorps 0610007D04Rik, anticorps Kal, anticorps Klk1b6, anticorps mGk-6, anticorps kallikrein 1, anticorps kallikrein 1 L homeolog, anticorps KLK1, anticorps klk1.L, anticorps LOC100101620, anticorps Klk1

Sujet:

Synonyms: Kallikrein-1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1

Tissue Specificity: Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.

Background: KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

UniProt: P06870

Pathways: Système du Complément