RPGR anticorps (AA 13-338)

N° du produit ABIN5693297

Détail du produit anti-RPGR anticorps

Antigène: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Épitope: AA 13-338

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPGR est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for RPGR detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human RPGR recombinant protein (Position: A13-F338).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur RPGR

Antigène: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Autre désignation: RPGR (RPGR Produits)

Synonymes: anticorps xrpgr, anticorps COD1, anticorps CORDX1, anticorps CRD, anticorps PCDX, anticorps RP15, anticorps RP3, anticorps XLRP3, anticorps orf15, anticorps Rp3h, anticorps retinitis pigmentosa GTPase regulator, anticorps retinitis pigmentosa GTPase regulator S homeolog, anticorps Rpgr, anticorps RPGR, anticorps rpgr, anticorps rpgr.S, anticorps Bm1_19935, anticorps NAEGRDRAFT_80250

Sujet:

Synonyms: X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3

Tissue Specificity: Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.

Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

UniProt: Q92834