Tryptophan Hydroxylase 1 anticorps (AA 1-111)
Aperçu rapide pour Tryptophan Hydroxylase 1 anticorps (AA 1-111) (ABIN5693317)
Antigène
Voir toutes Tryptophan Hydroxylase 1 (TPH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-111
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Fonction
- Anti-Tryptophan Hydroxylase/TPH1 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Tryptophan Hydroxylase/TPH1 Antibody (ABIN5693317). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human Tryptophan Hydroxylase recombinant protein (Position: M1-K111).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Tryptophan Hydroxylase 1 (TPH1)
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Autre désignation
- TPH1
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Sujet
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Synonyms: Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH
Tissue Specificity: Isoform 2 seems to be less widely expressed than isoform 1.
Background: Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
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Poids moléculaire
- 51 kDa
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ID gène
- 7166
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UniProt
- P17752
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Pathways
- Feeding Behaviour
Antigène
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