SFRP1 anticorps (C-Term)

N° du produit ABIN569588

L’anticorps anti-SFRP1 Polyclonal Chèvre est utilisé pour la détection de SFRP1 dans des échantillons de Humain, Souris et Boeuf (Vache). Il a été validé pour IHC (p) et EIA.

Aperçu rapide pour SFRP1 anticorps (C-Term) (ABIN569588)

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-SFRP1 anticorps

Épitope: C-Term

Séquence: KNHECPTFQS VFK

Specificité: Recognizes Secreted Frizzled-related Protein 1 (SFRP1) at C-term.

Réactivité croisée (Details): Species reactivity (expected):Bovine and Mouse.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Synthetic peptide corresponding to the C-terminus of Human SFRP1 (NP_003003.3).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: SFRP1

Sujet: SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.Synonyms: FRP, FRP-1, FRP1, SARP-2, SARP2, SFRP-1, Secreted apoptosis-related protein 2, Secreted frizzled-related protein 1

ID gène: 6422

NCBI Accession: NP_003003

UniProt: Q8N474

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation