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BIRC3 anticorps (Internal Region)
BIRC3
Reactivité: Humain, Rat
WB, EIA
Hôte: Chèvre
Polyclonal
unconjugated
Détail du produit anti-BIRC3 anticorps
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Antigène
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BIRC3
(Baculoviral IAP Repeat Containing 3 (BIRC3))
Épitope
Tous les épitopes à travers BIRC3 Anticorps.
Internal Region
Reactivité
Toutes les réactivités sur BIRC3 Anticorps
Humain, Rat
Hôte
Toutes les hôtes sur BIRC3 Anticorps
Chèvre
Clonalité
Toutes les clonalités sur BIRC3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers BIRC3 Anticorps
Cet anticorp BIRC3 est non-conjugé
Application
Tous les applications à travers BIRC3 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Séquence
C-SVNNLEATSQ P
Specificité
Recognizes BIRC3.
Réactivité croisée (Details)
Species reactivity (expected):Human. Species reactivity (tested):Rat.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogène
Peptide with sequence from the internal region of the protein sequence according to NP_001156.1. Genename: BIRC3
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Reconstitution
Reported variants represent identical protein: NP_892007.1, NP_001156.1.
Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur BIRC3
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Antigène
BIRC3
(Baculoviral IAP Repeat Containing 3 (BIRC3))
Autre désignation
IAP1 / BIRC3 (BIRC3 Produits )
Synonymes
anticorps AIP1, anticorps API2, anticorps CIAP2, anticorps HAIP1, anticorps HIAP1, anticorps MALT2, anticorps MIHC, anticorps RNF49, anticorps c-IAP2, anticorps Api1, anticorps Api2, anticorps IAP1, anticorps IAP2, anticorps MIHB, anticorps Birc2, anticorps HIAP2, anticorps MIAP1, anticorps MIAP2, anticorps cIAP1, anticorps cIAP2, anticorps cIAP-1, anticorps cIAP-2, anticorps AW107670, anticorps BIRC2, anticorps baculoviral IAP repeat containing 3, anticorps baculoviral IAP repeat-containing 3, anticorps baculoviral IAP repeat-containing protein 3, anticorps inhibitor of apoptosis protein-2, anticorps BIRC3, anticorps Birc3, anticorps LOC100399118, anticorps OpmnVgp074
Sujet
Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms.Synonyms: API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, HIAP-1, IAP homolog C, Inhibitor of apoptosis protein 1, MIHC, RING finger protein 49, RNF49, TNFR2-TRAF-signaling complex protein 1, cIAP2
ID gène
330
NCBI Accession
NP_001156
UniProt
Q13489
Pathways
Apoptose , Caspase Cascade in Apoptosis , Activation of Innate immune Response , Toll-Like Receptors Cascades
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