Isocitrate Dehydrogenase anticorps (Internal Region)

N° du produit ABIN569649

Cet anticorps anti-Isocitrate Dehydrogenase Polyclonal Chèvre (ABIN569649) détecte spécifiquement Isocitrate Dehydrogenase dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Chien, Mouton et Boeuf (Vache).

Aperçu rapide pour Isocitrate Dehydrogenase anticorps (Internal Region) (ABIN569649)

Antigène: Isocitrate Dehydrogenase (IDH)

Reactivité: Humain, Rat, Souris, Chien, Mouton, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Isocitrate Dehydrogenase est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Isocitrate Dehydrogenase anticorps

Épitope: AA 65-77, Internal Region

Séquence: KKHNVGVKCA TIT

Specificité: Recognizes IDH1 (65-77).

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Sheep.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_005887.2.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Isocitrate Dehydrogenase

Antigène: Isocitrate Dehydrogenase (IDH)

Autre désignation: Isocitrate Dehydrogenase / IDH

Sujet: IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Synonyms: Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD, cytoplasmic Isocitrate dehydrogenase [NADP]

Poids moléculaire: 46.7kDa (NP_005887.2).

ID gène: 3417

NCBI Accession: NP_005887

UniProt: O75874