ACTN1 anticorps (AA 272-490)

N° du produit ABIN5697056

L’anticorps Lapin Polyclonal anti-ACTN1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter ACTN1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ACTN1 anticorps (AA 272-490) (ABIN5697056)

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-ACTN1 anticorps

Épitope: AA 272-490

Fonction: ACTN1 antibody

Immunogène:

Immunogen sequence: 272-490aa

Immunogen: actinin, alpha 1

Isotype: IgG

Information d'application

Indications d'application: WB : 1:1000-1:10000 IHC : 1:50-1:500 IF : 1:50-1:500

Commentaires:

NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00322( a-Actinin Antibody) at dilution of 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ACTN1

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Autre désignation: ACTN1

Sujet:

Synonyms: Alpha-actinin-1|Alpha-actinin cytoskeletal isoform|F-actin cross-linking protein|Non-muscle alpha-actinin-1|ACTN1

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 103 kDa

UniProt: P12814

Pathways: Cell-Cell Junction Organization