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KCNK18 anticorps

Cet anticorps anti-KCNK18 est un anticorps Lapin Polyclonal détectant KCNK18 dans WB et ELISA. Adapté pour Humain.
N° du produit ABIN5698029

Aperçu rapide pour KCNK18 anticorps (ABIN5698029)

Antigène

Voir toutes KCNK18 Anticorps
KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Reactivité

  • 17
  • 10
  • 2
Humain

Hôte

  • 18
Lapin

Clonalité

  • 18
Polyclonal

Conjugué

  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp KCNK18 est non-conjugé

Application

  • 11
  • 8
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Fonction

    KCNK18 antibody

    Immunogène

    potassium channel, subfamily K, member 18

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

    Autre désignation

    KCNK18

    Sujet

    Synonyms: Potassium channel subfamily K member 18|TWIK-related individual potassium channel|TWIK-related spinal cord potassium channel|KCNK18|TRESK|TRIK

    Background: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity).

    Poids moléculaire

    44 kDa

    ID gène

    338567

    UniProt

    Q7Z418
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