KCNK18 anticorps
Aperçu rapide pour KCNK18 anticorps (ABIN5698029)
Antigène
Voir toutes KCNK18 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- KCNK18 antibody
-
Immunogène
- potassium channel, subfamily K, member 18
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
-
Autre désignation
- KCNK18
-
Sujet
-
Synonyms: Potassium channel subfamily K member 18|TWIK-related individual potassium channel|TWIK-related spinal cord potassium channel|KCNK18|TRESK|TRIK
Background: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity).
-
Poids moléculaire
- 44 kDa
-
ID gène
- 338567
-
UniProt
- Q7Z418
Antigène
-