KCNK18 anticorps

N° du produit ABIN5698029

Détail du produit anti-KCNK18 anticorps

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK18 est non-conjugé

Application: Western Blotting (WB), ELISA

Immunogène: potassium channel, subfamily K, member 18

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur KCNK18

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Autre désignation: KCNK18 (KCNK18 Produits)

Synonymes: anticorps K2p18.1, anticorps MGR13, anticorps TRESK, anticorps TRESK-2, anticorps TRESK2, anticorps TRIK, anticorps Gm781, anticorps Tresk, anticorps Tresk-2, anticorps Trik, anticorps potassium two pore domain channel subfamily K member 18, anticorps potassium channel, subfamily K, member 18, anticorps KCNK18, anticorps Kcnk18

Sujet: Synonyms:TRESK, TRIK Background:Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity).

Poids moléculaire: 44 kDa

ID gène: 338567

UniProt: Q7Z418