CBX3 anticorps

N° du produit ABIN5699705

L’anticorps Lapin Polyclonal anti-CBX3 a été validé pour WB, IHC, ELISA, IP et IF. Il convient pour détecter CBX3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CBX3 anticorps (ABIN5699705)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-CBX3 anticorps

Fonction: CBX3 antibody

Immunogène: chromobox homolog 3 (HP1 gamma homolog, Drosophila)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab01330(CBX3 antibody) at dilution of 1:500

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: CBX3

Sujet:

Synonyms: Chromobox protein homolog 3|HECH|Heterochromatin protein 1 homolog gamma (HP1 gamma)|Modifier 2 protein|CBX3

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Poids moléculaire: 22 kDa

ID gène: 11335

UniProt: Q13185