MAP1LC3A anticorps (AA 1-125)
Aperçu rapide pour MAP1LC3A anticorps (AA 1-125) (ABIN5700262)
Antigène
Voir toutes MAP1LC3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-125
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Fonction
- LC3 antibody
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Immunogène
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Immunogen sequence: 1-125aa
Immunogen: microtubule-associated protein 1 light chain 3 beta
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Chloroquine treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab04717(LC3 Antibody) at dilution of 1:1000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.1 % sodium azide and 50 % glycerol pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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Autre désignation
- LC3
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Sujet
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Synonyms: Microtubule-associated proteins 1A/1B light chain 3B|Autophagy-related protein LC3 B|Autophagy-related ubiquitin-like modifier LC3 B|MAP1 light chain 3-like protein 2|MAP1A/MAP1B light chain 3 B (MAP1A/MAP1B LC3 B)|Microtubule-associated protein 1 light chain 3 beta|MAP1LC3B|MAP1ALC3
Background: Map1LC3, also known as LC3, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. Three human Map1LC isoforms, MAP1LC3A, MAP1LC3B, and MAP1LC3C, undergo post-translational modifications during autophagy. And they differ in their post-translation modifications during autophagy. Map1LC3 also exists in two modified forms, an 18- kDa cytoplasmic form that was originally identified as a subunit of the microtubule-associated protein 1, and a 16- kDa form that is associated with the autophagosome membrane. This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C.
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Poids moléculaire
- 16 kDa
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Pathways
- Autophagy
Antigène
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