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COMT anticorps

L’anticorps Lapin Polyclonal anti-COMT a été validé pour WB, IHC, ELISA, IP, IF et FACS. Il convient pour détecter COMT dans des échantillons de Humain, Rat et Souris.
N° du produit ABIN5700530

Aperçu rapide pour COMT anticorps (ABIN5700530)

Antigène

Voir toutes COMT Anticorps
COMT (Catechol-O-Methyltransferase (COMT))

Reactivité

  • 57
  • 40
  • 40
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 66
  • 12
  • 3
  • 1
Lapin

Clonalité

  • 62
  • 20
Polyclonal

Conjugué

  • 50
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp COMT est non-conjugé

Application

  • 47
  • 26
  • 21
  • 16
  • 13
  • 13
  • 12
  • 8
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Fonction

    COMT antibody

    Immunogène

    catechol-O-methyltransferase

    Isotype

    IgG
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01856( COMT Antibody) at dilution of 1:600

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze / thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    -20°C for 12 months

    Date de péremption

    12 months
  • Antigène

    COMT (Catechol-O-Methyltransferase (COMT))

    Autre désignation

    COMT

    Sujet

    Synonyms: Catechol O-methyltransferase|COMT

    Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

    Poids moléculaire

    30 kDa

    ID gène

    1312

    UniProt

    P21964

    Pathways

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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