COMT anticorps
Aperçu rapide pour COMT anticorps (ABIN5700530)
Antigène
Voir toutes COMT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- COMT antibody
-
Immunogène
- catechol-O-methyltransferase
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab01856( COMT Antibody) at dilution of 1:600
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- COMT (Catechol-O-Methyltransferase (COMT))
-
Autre désignation
- COMT
-
Sujet
-
Synonyms: Catechol O-methyltransferase|COMT
Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.
-
Poids moléculaire
- 30 kDa
-
ID gène
- 1312
-
UniProt
- P21964
-
Pathways
- Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
Antigène
-