POLR2D anticorps

N° du produit ABIN5700753

Détail du produit anti-POLR2D anticorps

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2D est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogène: polymerase (RNA) II (DNA directed) polypeptide D

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Date de péremption: 12 months

Détails sur POLR2D

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Autre désignation: POLR2D (POLR2D Produits)

Synonymes: anticorps wu:fa95b11, anticorps zgc:110435, anticorps HSRBP4, anticorps HSRPB4, anticorps RBP4, anticorps RPB16, anticorps 2310002G05Rik, anticorps 2610028L19Rik, anticorps RNA polymerase II subunit D, anticorps DNA-directed RNA polymerase II 16 kDa polypeptide, anticorps polymerase (RNA) II (DNA directed) polypeptide D, anticorps Polr2d, anticorps CpipJ_CPIJ006734, anticorps UREG_01395, anticorps LOC100282338, anticorps polr2d, anticorps POLR2D

Sujet: Synonyms: Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA(By similarity).

ID gène: 5433

UniProt: O15514

Pathways: Regulatory RNA Pathways