KEAP1 anticorps (AA 378-486)

N° du produit ABIN5702287

Cet anticorps Lapin Polyclonal détecte spécifiquement KEAP1 dans WB, ELISA, IHC et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour KEAP1 anticorps (AA 378-486) (ABIN5702287)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KEAP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-KEAP1 anticorps

Épitope: AA 378-486

Fonction: KEAP1 antibody

Immunogène:

Immunogen sequence: 378-486aa

Immunogen: kelch-like ECH-associated protein 1

Isotype: IgG

Information d'application

Indications d'application: WB : 1:1000-1:10000 IP : 1:200-1:2000 IHC : 1:50-1:200

Commentaires:

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04516(KEAP1 antibody) at dilution of 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: KEAP1

Sujet:

Synonyms: Kelch-like ECH-associated protein 1|Cytosolic inhibitor of Nrf2 (INrf2)|Kelch-like protein 19|KEAP1|INRF2|KIAA0132|KLHL19

Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Poids moléculaire: 55-70 kDa

ID gène: 9817

UniProt: Q14145

Pathways: Maintenance of Protein Location