PFKM anticorps
Aperçu rapide pour PFKM anticorps (ABIN5703722)
Antigène
Voir toutes PFKM AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- PFKM antibody
-
Immunogène
- phosphofructokinase, muscle
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200 IF : 1:10-1:100
-
Commentaires
-
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab06341(PFKM antibody) at dilution of 1:800
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- -20°C for 12 months
-
Date de péremption
- 12 months
-
-
- PFKM (phosphofructokinase, Muscle (PFKM))
-
Autre désignation
- PFKM
-
Sujet
-
Synonyms: ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK, PFK-M)|6-phosphofructokinase type A|Phosphofructo-1-kinase isozyme A (PFK-A)|Phosphohexokinase|PFKM|PFKX
Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
-
Poids moléculaire
- 75-85 kDa
-
ID gène
- 5213
-
UniProt
- P08237
-
Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg
Antigène
-