MMP1 anticorps

N° du produit ABIN5703938

L’anticorps Lapin Polyclonal anti-MMP1 a été validé pour WB, IHC, ELISA, IF, IP et FACS. Il convient pour détecter MMP1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MMP1 anticorps (ABIN5703938)

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Détail du produit anti-MMP1 anticorps

Fonction: MMP1 antibody

Immunogène:

Immunogen sequence: 23- 215aa

Immunogen: matrix metallopeptidase 1 (interstitial collagenase)

Isotype: IgG

Information d'application

Indications d'application: WB : 1:200-1:2000 IP :1:500-1:5000 IHC : 1:100-1:400 IF : 1:20-1:200

Commentaires:

A549 cells were subjected to SDS PAGE followed by western blot with FNab05233(MMP1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MMP1

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Autre désignation: MMP1

Sujet:

Synonyms: Interstitial collagenase|Fibroblast collagenase|Matrix metalloproteinase-1 (MMP-1)|22 kDa interstitial collagenase|27 kDa interstitial collagenase|MMP1|CLG

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Poids moléculaire: 54 kDa,62 kDa

ID gène: 4312

UniProt: P03956