PCK1 anticorps
Aperçu rapide pour PCK1 anticorps (ABIN5704108)
Antigène
Voir toutes PCK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- PCK1 antibody
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Immunogène
- phosphoenolpyruvate carboxykinase 1 (soluble)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
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Autre désignation
- PCK1
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Sujet
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Synonyms: Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C)|Serine-protein kinase PCK1|PCK1|PEPCK1
Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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ID gène
- 5105
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UniProt
- P35558
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
Antigène
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