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Chromogranin A anticorps

Cet anticorps anti-Chromogranin A est un anticorps Lapin Monoclonal détectant Chromogranin A dans IHC (p). Adapté pour Humain.
N° du produit ABIN5707585

Aperçu rapide pour Chromogranin A anticorps (ABIN5707585)

Antigène

Voir toutes Chromogranin A (CHGA) Anticorps
Chromogranin A (CHGA)

Reactivité

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  • 91
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  • 15
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Humain

Hôte

  • 129
  • 128
  • 5
  • 1
Lapin

Clonalité

  • 157
  • 105
Monoclonal

Conjugué

  • 110
  • 18
  • 14
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  • 13
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  • 6
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  • 2
  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
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Cet anticorp Chromogranin A est non-conjugé

Application

  • 113
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  • 35
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

BGRAN2R
  • Purification

    Purified

    Pureté

    Protein A affinity chromatography

    Immunogène

    A recombinant human protein was used as the immunogen for the recombinant Chromogranin A antibody.

    Isotype

    IgG kappa
  • Indications d'application

    The stated application concentrations are suggested starting points. Titration of the recombinant Chromogranin A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    Restrictions

    For Research Use only
  • Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the recombinant Chromogranin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Antigène

    Chromogranin A (CHGA)

    Autre désignation

    Chromogranin A

    Sujet

    Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins, i.e., it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in pancreas. Chromogranin A is the precursor to several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). [Wiki]

    Pathways

    Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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