MUC6 anticorps

N° du produit ABIN5707610

Détail du produit anti-MUC6 anticorps

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: A peptide from the Mucin-6 tandem repeat sequence was used as the immunogen for the recombinant MUC6 antibody.

Clone: MUCN6-2R

Isotype: IgG kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the recombinant MUC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant MUC6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MUC6

Antigène: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Autre désignation: MUC6 / Gastric Mucin (MUC6 Produits)

Synonymes: anticorps gastric, anticorps MUC-6, anticorps mucin-6-like, anticorps mucin 6, oligomeric mucus/gel-forming, anticorps mucin 6, gastric, anticorps LOC100850574, anticorps MUC6, anticorps Muc6

Sujet: MUC6 or gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.