NAPSA anticorps (AA 189-299)

N° du produit ABIN5707670

Cet anticorps Lapin Monoclonal détecte spécifiquement NAPSA dans IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour NAPSA anticorps (AA 189-299) (ABIN5707670)

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NAPSA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: NAPSA-1865R

Détail du produit anti-NAPSA anticorps

Épitope: AA 189-299

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: A recombinant fragment from the human protein (amino acids 189-299) was used as the immunogen for the recombinant Napsin A antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the recombinant Napsin A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Napsin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NAPSA

Antigène: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Autre désignation: Napsin A

Sujet: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis