CD79a anticorps (AA 202-216)

N° du produit ABIN5707841

Cet anticorps Lapin Monoclonal détecte spécifiquement CD79a dans IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CD79a anticorps (AA 202-216) (ABIN5707841)

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD79a est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDLA79a-3R

Détail du produit anti-CD79a anticorps

Épitope: AA 202-216

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the CD79a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant CD79a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD79a

Antigène: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Autre désignation: CD79a

Sujet: The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). CD79a plays multiple and diverse roles in B cell development and function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with the immunoglobulin light chain and the pre-BCR when associated with the surrogate light chain in developing B cells. Association of the CD79a/b heterodimer with the immunoglobulin heavy chain is required for surface expression of the BCR and BCR induced calcium flux and protein tyrosine phosphorylation. [Wiki]

Pathways: BCR Signaling