MYOD1 anticorps

N° du produit ABIN5708000

Cet anticorps Lapin Monoclonal détecte spécifiquement MYOD1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MYOD1 anticorps (ABIN5708000)

Antigène: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MYOD1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MYOD1-2075R

Détail du produit anti-MYOD1 anticorps

Purification: Purified

Pureté: Protein A affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this recombinant MyoD antibody.

Isotype: IgG kappa

Information d'application

Indications d'application: The optimal dilution of the recombinant MyoD antibody for each application should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant MyoD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MYOD1

Antigène: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Autre désignation: MyoD1

Sujet: MyoD, or MYOD1, is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. The effect of MyoD on satellite cells is dose-dependent, high MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. This is likely due to functional redundancy from Myf5 and/or Mrf4. Nevertheless, the combination of MyoD and Myf5 is vital to the success of myogenesis. [Wiki]

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development