EPO anticorps

N° du produit ABIN5708355

L’anticorps Lapin Polyclonal anti-EPO a été validé pour WB et ELISA (Capture). Il convient pour détecter EPO dans des échantillons de Souris.

Aperçu rapide pour EPO anticorps (ABIN5708355)

Antigène: EPO (Erythropoietin (EPO))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPO est non-conjugé

Application: Western Blotting (WB), ELISA (Capture)

Détail du produit anti-EPO anticorps

Purification: Antigen affinity purified

Immunogène: A recombinant mouse protein corresponding to amino acids D34-R192 was used as the immunogen for the Erythropoietin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Erythropoietin antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL (mouse protein tested)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Erythropoietin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur EPO

Antigène: EPO (Erythropoietin (EPO))

Autre désignation: Erythropoietin

Classe de substances: Hormone

Sujet: The EPO gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

UniProt: P01588

Pathways: Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity