ABCE1 anticorps (AA 419-599)

N° du produit ABIN5708515

Cet anticorps anti-ABCE1 Polyclonal Lapin (ABIN5708515) détecte spécifiquement ABCE1 dans WB, FACS, IF et IP. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ABCE1 anticorps (AA 419-599) (ABIN5708515)

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCE1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-ABCE1 anticorps

Épitope: AA 419-599

Fonction: ABCE1 Antibody

Purification: Antigen affinity

Immunogène: Amino acids K419-D599 from the human protein were used as the immunogen for the ABCE1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Differences in protocols and secondary/substrate sensitivity may require the ABCE1 antibody to be titrated for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ABCE1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ABCE1

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Autre désignation: ABCE1 / ATP binding cassette E1

Sujet: ATP binding cassette E1 (ABCE1, also called RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

UniProt: P61221