ABCE1 anticorps (AA 141-599)

N° du produit ABIN7870676

Cet anticorps Lapin Polyclonal détecte spécifiquement ABCE1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour ABCE1 anticorps (AA 141-599) (ABIN7870676)

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ABCE1 anticorps

Épitope: AA 141-599

Fonction: Zebrafish ATP binding cassette E1 Antibody / Abce1

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish ABCE1 recombinant protein (amino acids Q141-D599) was used as the immunogen for the Zebrafish ATP binding cassette E1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish ATP binding cassette E1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish ATP binding cassette E1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ABCE1

Antigène: ABCE1 (RLI1) (ABC Transporter E Family Member 1 (RLI1))

Autre désignation: ATP binding cassette E1

Sujet: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

UniProt: Q6TNW3