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PRNP anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement PRNP dans WB, IHC et IHC (p). Il présente une réactivité envers Humain.
N° du produit ABIN574438

Aperçu rapide pour PRNP anticorps (ABIN574438)

Antigène

Voir toutes PRNP Anticorps
PRNP (Prion Protein (PRNP))

Reactivité

  • 122
  • 70
  • 54
  • 20
  • 13
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 106
  • 30
  • 16
  • 2
  • 2
  • 1
Souris

Clonalité

  • 79
  • 78
Monoclonal

Conjugué

  • 60
  • 11
  • 9
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp PRNP est non-conjugé

Application

  • 75
  • 38
  • 35
  • 27
  • 26
  • 19
  • 15
  • 15
  • 14
  • 9
  • 7
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

EM-20
  • Specificité

    The mouse monoclonal antibody EM-20 recognizes human prion protein (PrP). Diglycosylated form of PrP has ~40 kD, monoglycosylated form ~30 kD, and nonglycosylated form ~19-21 kD. This antibody is suitable for discrimination between normal cellular prion protein (PrPc) and its conformationally changed form (PrPSc) prion protein.

    Purification

    Protein A purified

    Immunogène

    Recombinant human prion protein.

    Type of Immunogen: Recombinant protein

    Isotype

    IgG2a
  • Indications d'application

    Approved: IHC, IHC-P (10 μg/mL), WB (0.5 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody,

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 15 mM sodium azide,  pH 7.4

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    avoid freeze thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
  • Antigène

    PRNP (Prion Protein (PRNP))

    Autre désignation

    PRNP / PrP / Prion

    Sujet

    Name/Gene ID: PRNP

    Synonyms: PRNP, AltPrP, ASCR, CD230 antigen, CJD, KURU, Major prion protein, p27-30, Prion, Prion-related protein, PRIP, Prion protein (p27-30), PrP, PrP33-35C, BSE, CD230, Prion protein, PrP27-30, PrPc

    ID gène

    5621

    UniProt

    P04156

    Pathways

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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