Cathepsin S anticorps (AA 17-331)

N° du produit ABIN5775924

Cet anticorps Souris Monoclonal détecte spécifiquement Cathepsin S dans WB, ELISA, ICC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Cathepsin S anticorps (AA 17-331) (ABIN5775924)

Antigène: Cathepsin S (CTSS)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cathepsin S est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT1F9

Détail du produit anti-Cathepsin S anticorps

Épitope: AA 17-331

Fonction: Human Cathepsin S antibody

Purification: Purified

Immunogène: Recombinant human CTSS (17-331aa) purified from E. coli

Isotype: IgG2b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing cycles

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur Cathepsin S

Antigène: Cathepsin S (CTSS)

Autre désignation: Cathepsin S

Sujet: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

NCBI Accession: NP_004070

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades