SBDS anticorps (AA 1-250)

N° du produit ABIN5775988

L’anticorps Souris Monoclonal anti-SBDS a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter SBDS dans des échantillons de Humain.

Aperçu rapide pour SBDS anticorps (AA 1-250) (ABIN5775988)

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SBDS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1E8

Détail du produit anti-SBDS anticorps

Épitope: AA 1-250

Immunogène: Recombinant human SBDS (1-250aa) purified from E. coli

Isotype: IgG2b kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur SBDS

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Autre désignation: SBDS

Sujet: The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.

NCBI Accession: NP_057122

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly