PA2G4 anticorps (AA 1-394)

N° du produit ABIN5776098

Cet anticorps Souris Monoclonal détecte spécifiquement PA2G4 dans WB, ELISA, IF, FACS et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour PA2G4 anticorps (AA 1-394) (ABIN5776098)

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PA2G4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: AT5E7

Détail du produit anti-PA2G4 anticorps

Épitope: AA 1-394

Immunogène: Recombinant human PA2G4 (1-394aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur PA2G4

Antigène: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Autre désignation: PA2G4

Sujet: PA2G4 may play a role in a ERBB3-regulated signal transduction pathway and seems be involved in growth regulation. This protein acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Also, this protein Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity, and binds RNA. The protein is associated with 28S, 18S and 5. 8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA, that may be involved in regulation of intermediate and late steps of rRNA processing, and may be involved in ribosome assembly. The protein mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity), and regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

NCBI Accession: NP_006182

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades