GPI anticorps (AA 1-558)
Aperçu rapide pour GPI anticorps (AA 1-558) (ABIN5776107)
Antigène
Voir toutes GPI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-558
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Immunogène
- Recombinant human GPI (1-558aa) purified from E. coli
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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Autre désignation
- GPI
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Sujet
- Glucose-6-phosphate isomerase (GPI), also known as phosphoglucose isomerase (PGI) or phosphohexose isomerase (PHI), is an enzyme. In the cytoplasm, it functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate (G6P) and fructose-6-phosphate (F6P). Extracellularly, it functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. GPI is also referred to as autocrine motility factor (AMF) based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in GPI are the cause of nonspherocytic hemolytic anemia, and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.
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NCBI Accession
- NP_000166
Antigène
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