SGTA anticorps (AA 1-313)

N° du produit ABIN5776127

Cet anticorps anti-SGTA est un anticorps Souris Monoclonal détectant SGTA dans WB, ELISA, IF et ICC. Adapté pour Humain.

Aperçu rapide pour SGTA anticorps (AA 1-313) (ABIN5776127)

Antigène: SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SGTA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT19E8

Détail du produit anti-SGTA anticorps

Épitope: AA 1-313

Fonction: Human SGTA antibody

Purification: Purified

Immunogène: Recombinant human SGTA (1-313aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur SGTA

Antigène: SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))

Autre désignation: SGTA

Sujet: SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protein is believed to function as a component of the androgen receptor (AR) -chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances.

NCBI Accession: NP_003012