TXNRD1 anticorps (AA 161-647)
Aperçu rapide pour TXNRD1 anticorps (AA 161-647) (ABIN5776265)
Antigène
Voir toutes TXNRD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 161-647
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Immunogène
- Recombinant human TXNRD1 (161-647aa) purified from E. coli
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Isotype
- IgG2b kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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Autre désignation
- Thioredoxin Reductase 1/TRXR1
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Sujet
- TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
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NCBI Accession
- NP_001087240
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
Antigène
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