FH anticorps (AA 44-510)
Aperçu rapide pour FH anticorps (AA 44-510) (ABIN5776268)
Antigène
Voir toutes FH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 44-510
-
Immunogène
- Recombinant human Fumarase (44-510aa) purified from E. coli
-
Isotype
- IgG2a kappa
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Stock
- 4 °C,-20 °C,-80 °C
-
Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
-
- FH (Fumarate Hydratase (FH))
-
Autre désignation
- Fumarase/FH
-
Sujet
- Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.
-
NCBI Accession
- NP_000134
Antigène
-