RAD51 anticorps (Tyr315)

N° du produit ABIN5958191

Cet anticorps Lapin Polyclonal détecte spécifiquement RAD51 dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour RAD51 anticorps (Tyr315) (ABIN5958191)

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RAD51 anticorps

Épitope: Tyr315

Specificité: BRCA1/BRCA2 containing complex,subunit 5,BRCC 5,BRCC5,DNA repair protein RAD51 homolog 1,DNA repair protein rhp51,FANCR,hRAD51,HsRAD51,HsT16930,MRMV2,Rad 51,RAD51,RAD51 homolog (RecA homolog,E. coli) (S. cerevisiae),RAD51 homolog A,RAD51 homolog,RAD51 recombinase,RAD51,S. cerevisiae,homolog of,RAD51,RAD51A,RECA,RecA like protein,RecA,E. coli,homolog of,Recombination protein A

Purification: Affinity purification

Immunogène: Synthesized peptide derived from human Rad51 around the non-phosphorylation site of Tyr315.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD51

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: Rad51

Sujet: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, whicHuman, Mouseay be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 37kDa

ID gène: 5888

UniProt: Q06609

Pathways: Réparation de l'ADN