Myosin VI anticorps

N° du produit ABIN5958676

Cet anticorps anti-Myosin VI Polyclonal Lapin (ABIN5958676) détecte spécifiquement Myosin VI dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Myosin VI anticorps (ABIN5958676)

Antigène: Myosin VI (MYO6)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myosin VI est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Myosin VI anticorps

Specificité: Deafness autosomal recessive 37,DFNA 22,DFNA22,DFNB 37,DFNB37,KIAA0389,MYO 6,Myo6,MYO6,Myosin VI,Myosin-VI,Myosin6,Unconventional myosin-6,Unconventional myosin-VI

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the N-terminal region of human Myosin VI

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:5000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Myosin VI

Antigène: Myosin VI (MYO6)

Autre désignation: Myosin VI

Sujet: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. MYO6 (Myosin VI) is a Protein Coding gene. Diseases associated with MYO6 include Deafness, Autosomal Dominant 22 and Deafness, Autosomal Recessive 37. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is MYO7A.

Poids moléculaire: 150kDa

ID gène: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization