CD40 anticorps

N° du produit ABIN610078

Cet anticorps Souris Monoclonal détecte spécifiquement CD40 dans FACS, ELISA, IP et Func. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour CD40 anticorps (ABIN610078)

Antigène: CD40

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: BE-1

Détail du produit anti-CD40 anticorps

Specificité: CD40 Molecule of about 44 kd.

Purification: Protein A purified

Immunogène: Murine L cells transfectants expressing human CD40.

Type of Immunogen: Cells

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, IP

Usage: Function: Binding of cross linked BE-1 will partially activate B cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Agent conservateur: Azide free

Conseil sur la manipulation: Do not freeze. Open under aseptic conditions.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Open under aseptic conditions.

Références pour anticorps anti-CD40 (ABIN610078)

Danen, Sonneveld, Brakebusch, Fassler, Sonnenberg: "The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis." dans: The Journal of cell biology, Vol. 159, Issue 6, pp. 1071-86, (2002) (PubMed).

Rhee, Sen, Lu, Wu, Leoni, Rubin, Corr, Carson: "Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas." dans: Oncogene, Vol. 21, Issue 43, pp. 6598-605, (2002) (PubMed).

Chen, Mosher: "Formation of sodium dodecyl sulfate-stable fibronectin multimers. Failure to detect products of thiol-disulfide exchange in cyanogen bromide or limited acid digests of stabilized matrix fibronectin." dans: The Journal of biological chemistry, Vol. 271, Issue 15, pp. 9084-9, (1996) (PubMed).

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

ID gène: 958

UniProt: P25942

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints