CD70 anticorps (PE)

N° du produit ABIN610197

Détail du produit anti-CD70 anticorps (PE)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est conjugé à/à la PE

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

Specificité: CD70 Molecule of approximately 30 kd.

Purification: Gel filtration

Immunogène: Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.

Clone: BU69

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells. One test is 1.6 μL per 5 x 10e5 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Product is photosensitive and should be protected from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Références pour anticorps anti-CD70 (PE) (ABIN610197)

MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." dans: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).

Arnold, Seifert, Asadullah, Volk: "Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7140-7, (1999) (PubMed).

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70 (CD70 Produits)

Synonymes: anticorps CD27LG, anticorps Cd27l, anticorps Tnfsf7, anticorps CD27L, anticorps TNFSF7, anticorps CD70 antigen, anticorps CD70 molecule, anticorps Cd70 molecule, anticorps Cd70, anticorps CD70

Sujet: Name/Gene ID: CD70
Family: TNF

Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints