CD70 anticorps

N° du produit ABIN610198

Cet anticorps Souris Monoclonal détecte spécifiquement CD70 dans ELISA, FACS, IHC, IHC (fro), ICC et Func. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour CD70 anticorps (ABIN610198)

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

Clone: BU69

Détail du produit anti-CD70 anticorps

Specificité: CD70 Molecule of approximately 30 kd.

Purification: Protein A purified

Immunogène: Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Agent conservateur: Azide free

Conseil sur la manipulation: Do not freeze. Open under aseptic conditions.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Open under aseptic conditions.

Références pour anticorps anti-CD70 (ABIN610198)

MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." dans: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).

Arnold, Seifert, Asadullah, Volk: "Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7140-7, (1999) (PubMed).

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70

Sujet: Name/Gene ID: CD70
Family: TNF

Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints