Perforin 1 anticorps (PE)

N° du produit ABIN610399

Cet anticorps Souris Monoclonal détecte spécifiquement Perforin 1 dans IHC, FACS et IHC (fro). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour Perforin 1 anticorps (PE) (ABIN610399)

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Perforin 1 est conjugé à/à la PE

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: Delta G9

Détail du produit anti-Perforin 1 anticorps (PE)

Specificité: Human perforin molecule of 70 kd.

Purification: Gel filtration

Immunogène: Purified (With Antibiotics) granules from human YT lymphoma cell line.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Approved: Flo, IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze. Product is photosensitive and should be protected from light.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze. Protect from light.

Références pour anticorps anti-Perforin 1 (PE) (ABIN610399)

Chang, Xing, Pan, Algeciras-Schimnich, Barnhart, Yaish-Ohad, Peter, Yang: "c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis." dans: The EMBO journal, Vol. 21, Issue 14, pp. 3704-14, (2002) (PubMed).

MacFarlane, Harper, Snowden, Dyer, Barnett, Pringle, Cohen: "Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia." dans: Oncogene, Vol. 21, Issue 44, pp. 6809-18, (2002) (PubMed).

Détails sur Perforin 1

Antigène: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Autre désignation: PRF1 / Perforin

Sujet: Name/Gene ID: PRF1

Synonyms: PRF1, HPLH2, Perforin, p1, Perforin1, PFP, Cytolysin, FLH2, Perforin-1

ID gène: 5551

UniProt: P14222

Pathways: Apoptose, Caspase Cascade in Apoptosis