GRK1 anticorps (AA 1-160)

N° du produit ABIN6134352

Cet anticorps anti-GRK1 est un anticorps Lapin Polyclonal détectant GRK1 dans WB, IHC et IF. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour GRK1 anticorps (AA 1-160) (ABIN6134352)

Antigène: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GRK1 anticorps

Épitope: AA 1-160

Séquence: MDFGSLETVV ANSAFIAARG SFDGSSSQPS RDKKYLAKLK LPPLSKCESL RDSLSLEFES VCLEQPIGKK LFQQFLQSAE KHLPALELWK DIEDYDTADN DLQPQKAQTI LAQYLDPQAK LFCSFLDEGI VAKFKEGPVE IQDGLFQPLL QATLAHLGQA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1 (NP_002920.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-GRK1 (ABIN6134352)

Liu, Chen, Yu, Raghupathy, Liu, Qin, Li, Huang, Liao, Wang, Zou, Shu, Tang, Liu: "Knockout of RP2 decreases GRK1 and rod transducin subunits and leads to photoreceptor degeneration in zebrafish." dans: Human molecular genetics, Vol. 24, Issue 16, pp. 4648-59, (2015) (PubMed).

Détails sur GRK1

Antigène: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Autre désignation: GRK1

Sujet: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).,GRK1,GPRK1,RHOK,RK,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Tyrosine kinases,Neuroscience,GRK1

Poids moléculaire: 63 kDa

ID gène: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction