ALOXE3 anticorps (AA 1-280)

N° du produit ABIN6136820

Cet anticorps anti-ALOXE3 est un anticorps Lapin Polyclonal détectant ALOXE3 dans WB. Adapté pour Humain.

Aperçu rapide pour ALOXE3 anticorps (AA 1-280) (ABIN6136820)

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOXE3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ALOXE3 anticorps

Épitope: AA 1-280

Séquence: MAVYRLCVTT GPYLRAGTLD NISVTLVGTC GESPKQRLDR MGRDFAPGSV QKYKVRCTAE LGELLLLRVH KERYAFFRKD SWYCSRICVT EPDGSVSHFP CYQWIEGYCT VELRPGTART ICQDSLPLLL DHRTRELRAR QECYRWKIYA PGFPCMVDVN SFQEMESDKK FALTKTTTCV DQGDSSGNRY LPGFPMKIDI PSLMYMEPNV RYSATKTISL LFNAIPASLG MKLRGLLDRK GSWKKLDDMQ NIFWCHKTFT TKYVTEHWCE DHFFGYQYLN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALOXE3 (NP_067641.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALOXE3

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Autre désignation: ALOXE3

Sujet: This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.,ALOXE3,ARCI3,E-LOX,eLOX-3,eLOX3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,ALOXE3

Poids moléculaire: 80 kDa/95 kDa

ID gène: 59344

UniProt: Q9BYJ1

Pathways: Cell-Cell Junction Organization