Amphiregulin anticorps (AA 20-252)

N° du produit ABIN6137065

Cet anticorps Lapin Polyclonal détecte spécifiquement Amphiregulin dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Amphiregulin anticorps (AA 20-252) (ABIN6137065)

Antigène: Amphiregulin (AREG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Amphiregulin anticorps

Épitope: AA 20-252

Séquence: SGHYAAGLDL NDTYSGKREP FSGDHSADGF EVTSRSEMSS GSEISPVSEM PSSSEPSSGA DYDYSEEYDN EPQIPGYIVD DSVRVEQVVK PPQNKTESEN TSDKPKRKKK GGKNGKNRRN RKKKNPCNAE FQNFCIHGEC KYIEHLEAVT CKCQQEYFGE RCGEKSMKTH SMIDSSLSKI ALAAIAAFMS AVILTAVAVI TVQLRRQYVR KYEGEAEERK KLRQENGNVH AIA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 20-252 of human AREG (NP_001648.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: AREG

Sujet: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions.,AREG,AR,AREGB,CRDGF,SDGF,amphiregulin,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,AREG

Poids moléculaire: 27 kDa

ID gène: 374

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway