Asialoglycoprotein Receptor 1 anticorps (AA 1-150)
Aperçu rapide pour Asialoglycoprotein Receptor 1 anticorps (AA 1-150) (ABIN6137179)
Antigène
Voir toutes Asialoglycoprotein Receptor 1 (ASGR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-150
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Séquence
- MTKEYQDLQH LDNEESDHHQ LRKGPPPPQP LLQRLCSGPR LLLLSLGLSL LLLVVVCVIG SQNSQLQEEL RGLRETFSNF TASTEAQVKG LSTQGGNVGR KMKSLESQLE KQQKDLSEDH SSLLLHVKQF VSDLRSLSCQ MAALQGNGSE
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human ASGR1 (NP_001662.1).
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Isotype
- IgG
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Indications d'application
- WB,1:1000 - 1:4000,IHC,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Asialoglycoprotein Receptor 1 (ASGR1)
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Autre désignation
- ASGR1
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Sujet
- This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ASGR1,ASGPR,ASGPR1,CLEC4H1,HL-1,Signal Transduction,ASGR1
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Poids moléculaire
- 29 kDa/33 kDa
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ID gène
- 432
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UniProt
- P07306
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Pathways
- Thyroid Hormone Synthesis
Antigène
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