ATG9A anticorps (AA 180-290)

N° du produit ABIN6137269

L’anticorps Lapin Polyclonal anti-ATG9A a été validé pour WB. Il convient pour détecter ATG9A dans des échantillons de Humain.

Aperçu rapide pour ATG9A anticorps (AA 180-290) (ABIN6137269)

Antigène: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG9A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATG9A anticorps

Épitope: AA 180-290

Séquence: WQEVQARIVQ TQKEHQICIH KRELTELDIY HRILRFQNYM VALVNKSLLP LRFRLPGLGE AVFFTRGLKY NFELILFWGP GSLFLNEWSL KAEYKRGGQR LELAQRLSNR I

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human ATG9A (NP_076990.4).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ATG9A

Antigène: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Autre désignation: ATG9A

Sujet: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB in a process dependent on ARFIP2, but not ARFIP1. In addition to autophagy, also plays a role in necrotic cell death (By similarity.,ATG9A,APG9L1,MGD3208,mATG9,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,ATGs,ATG9A

Poids moléculaire: 60 kDa/87 kDa/94 kDa

ID gène: 79065

UniProt: Q7Z3C6