BAP1 anticorps (AA 460-729)

N° du produit ABIN6137447

Cet anticorps Lapin Polyclonal détecte spécifiquement BAP1 dans WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour BAP1 anticorps (AA 460-729) (ABIN6137447)

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-BAP1 anticorps

Épitope: AA 460-729

Séquence: SIPLSIKTSS GAGSPAVAVP THSQPSPTPS NESTDTASEI GSAFNSPLRS PIRSANPTRP SSPVTSHISK VLFGEDDSLL RVDCIRYNRA VRDLGPVIST GLLHLAEDGV LSPLALTEGG KGSSPSIRPI QGSQGSSSPV EKEVVEATDS REKTGMVRPG EPLSGEKYSP KELLALLKCV EAEIANYEAC LKEEVEKRKK FKIDDQRRTH NYDEFICTFI SMLAQEGMLA NLVEQNISVR RRQGVSIGRL HKQRKPDRRK RSRPYKAKRQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 460-729 of human BAP1 (NP_004647.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BAP1

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Autre désignation: BAP1

Sujet: This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.,BAP1,HUCEP-13,UCHL2,hucep-6,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Ubiquitin,BAP1

Poids moléculaire: 80 kDa

ID gène: 8314

UniProt: Q92560