BAP1 anticorps (AA 191-326)

N° du produit ABIN6940957

Détail du produit anti-BAP1 anticorps

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Épitope: AA 191-326

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAP1 est non-conjugé

Application: ELISA, Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)

Clone: BAP1-2431

Isotype: IgG2c kappa

Information d'application

Indications d'application:

Positive Control: Jurkat or PC-3 or HepG2 cells. Testis, Placenta, Ovarian or Breast Carcinoma.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur BAP1

Antigène: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Autre désignation: BAP1 (BAP1 Produits)

Synonymes: anticorps HUCEP-13, anticorps UCHL2, anticorps BAIAP3, anticorps 2300006C11Rik, anticorps AA989761, anticorps AW553466, anticorps mKIAA0272, anticorps uch-x4, anticorps hucep-13, anticorps hucep-6, anticorps uchl2, anticorps si:dkey-42i9.9, anticorps BRCA1 associated protein 1, anticorps Brca1 associated protein 1, anticorps BRCA1 associated protein 1 L homeolog, anticorps BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase), anticorps BAP1, anticorps Bap1, anticorps bap1.L, anticorps bap1

Sujet: The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.

Poids moléculaire: 91kDa

ID gène: 8314

UniProt: Q92560