BCAS3 anticorps (AA 674-913)

N° du produit ABIN6137481

Cet anticorps anti-BCAS3 est un anticorps Lapin Polyclonal détectant BCAS3 dans IHC, WB, IP et IF. Adapté pour Humain.

Aperçu rapide pour BCAS3 anticorps (AA 674-913) (ABIN6137481)

Antigène: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAS3 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-BCAS3 anticorps

Épitope: AA 674-913

Séquence: LAGLVPPGSP GPITRHGSYD SLASDHSGQE DEEWLSQVEI VTHTGPHRRL WMGPQFQFKT IHPSGQTTVI SSSSSVLQSH GPSDTPQPLL DFDTDDLDLN SLRIQPVRSD PVSMPGSSRP VSDRRGVSTV IDAASGTFDR SVTLLEVCGS WPEGFGLRHM SSMEHTEEGL RERLADAMAE SPSRDVVGSG TELQREGSIE TLSNSSGSTS GSIPRNFDGY RSPLPTNESQ PLSLFPTGFP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_060149.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BCAS3

Antigène: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Autre désignation: BCAS3

Sujet: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity. Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. Plays a regulatory role in autophagic activity. In complex with PHAF1, associates with the preautophagosomal structure during both non-selective and selective autophagy. Probably binds phosphatidylinositol 3-phosphate (PtdIns3P which would mediate the recruitment preautophagosomal structures.,BCAS3,GAOB1,MAAB,Cancer,Tumor biomarkers,Stem Cells,Cancer Stem Cells,BCAS3

Poids moléculaire: 74 kDa/99 kDa/101 kDa/102 kDa/103 kDa

ID gène: 54828

UniProt: Q9H6U6