BMP4 anticorps (AA 1-408)

N° du produit ABIN6137600

Détail du produit anti-BMP4 anticorps

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Épitope: AA 1-408

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRRRRA KRSPKHHSQR ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-408 of human BMP4 (NP_570912.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BMP4

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP4 (BMP4 Produits)

Synonymes: anticorps BMP2B, anticorps BMP2B1, anticorps MCOPS6, anticorps OFC11, anticorps ZYME, anticorps Bmp-4, anticorps Bmp2b, anticorps Bmp2b-1, anticorps Bmp2b1, anticorps BOMPR4A, anticorps bmp-4, anticorps zbmp-4, anticorps zgc:100779, anticorps BMP-4, anticorps XBMP-4, anticorps bmp2b, anticorps bmp2b1, anticorps bmp4, anticorps ofc11, anticorps xbmp4, anticorps zyme, anticorps BMP4, anticorps bone morphogenetic protein 4, anticorps bone morphogenetic protein 4 L homeolog, anticorps bone morphogenetic protein 4 S homeolog, anticorps BMP4, anticorps Bmp4, anticorps bmp4, anticorps bmp4.L, anticorps bmp4.S

Sujet: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.,BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Angiogenesis,Ligand,BMP4

Poids moléculaire: 46 kDa

ID gène: 652

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development